Unlock the World's Knowledge

Access authoritative information through advanced search, conversational AI, developer APIs, and direct model integration.

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Powerful Search Across Diverse Sources

Query millions of documents from humanity's most valuable knowledge repositories.

Scholar Publications

30M+ writings spanning multiple disciplines

Books

3 million+ publicly available books covering topics from history to technology

Magazines

Daily human art spanning various epochs and topics

Manuals

Comprehensive guides on various appliances, cars, and more

PubMed

The most advanced medical database in the world

USPTO

Inventions data over many years

Wikipedia

Live articles covering every facet of humanity

Front page of the Internet

Flow of messages from the largest chatting media app

Conversational Search Interface

Interact with knowledge naturally. Ask questions and get synthesized answers from our vast data sources.

what are first-line drugs against breast cancer?

HR+/HER2- Advanced Breast Cancer Treatment...

MDPI AG 1 · 2023

The Role of Human Epidermal Growth Factor Receptor 2...

Cureus 2 · 2024

Taxanes versus S-1 as the first-line chemotherapy for...

Tsutomu Takashima... 3 · 2015

+3 Sources

Answer

The first-line drugs against breast cancer include:
Endocrine therapy (ET) ET with tamoxifen, aromatase inhibitors (AIs; anastrozole, exemestane, or letrozole), or fulvestrant (combined with ovarian suppression in premenopausal women) for hormone receptor-positive (HR+), human epidermal growth factor receptor-2-negative (HER2–) breast cancer 1 . Trastuzumab (Herceptin) The first HER2-targeted medication, a monoclonal antibody that targets the HER2 receptor in HER2-positive breast cancer 2 . Ado-trastuzumab emtansine (T-DM1), an antibody-drug conjugate (ADC) that combines trastuzuman...

Direct Model Integration (MCP)

Enable language models to interact directly with our knowledge sources using the Model Context Protocol (MCP).

Integrate with local LLMs via MCP: Use our public endpoint https://mcp.spacefrontiers.org or self-host. For self-hosting, clone the server:

git clone https://github.com/SpaceFrontiers/mcp.git

Both methods require an API key, available from the API Keys page.

Configure the Claude Desktop App (claude_desktop_config.json) to use your self-hosted server (replace paths and API key):

{
  "mcpServers": {
    "Space Frontiers MCP server": {
      "command": "/path/to/your/uv",
      "args": [
        "run",
        "--with", "izihawa-loglib",
        "--with", "mcp[cli]",
        "--with", "spacefrontiers-clients",
        "mcp", "run",
        "/path/to/cloned/mcp/repo/mcp_server.py"
      ],
      "env": {
        "SPACE_FRONTIERS_API_KEY": "YOUR_API_KEY_HERE"
      }
    }
  }
}

Find more details and the server code on GitHub.

Developer API Access

Integrate Space Frontiers' knowledge capabilities into your own applications with our straightforward REST API.

$curl -X POST https://spacefrontiers.com/api/v1/search \

-H 'Authorization: Bearer YOUR_API_KEY' \

-H 'Content-Type: application/json' \

-d '{ "query": "latest news on AI", "sources": ["telegram"] }'

{
  "search_documents": [...],
  "count": 15,
  "has_next": true
}

View API Documentation →