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what are first-line drugs against breast cancer?

HR+/HER2- Advanced Breast Cancer Treatment...

MDPI AG 1 · 2023

The Role of Human Epidermal Growth Factor Receptor 2...

Cureus 2 · 2024

Taxanes versus S-1 as the first-line chemotherapy for...

Tsutomu Takashima... 3 · 2015

+3 Sources

Answer

The first-line drugs against breast cancer include:
Endocrine therapy (ET) ET with tamoxifen, aromatase inhibitors (AIs; anastrozole, exemestane, or letrozole), or fulvestrant (combined with ovarian suppression in premenopausal women) for hormone receptor-positive (HR+), human epidermal growth factor receptor-2-negative (HER2–) breast cancer 1 . Trastuzumab (Herceptin) The first HER2-targeted medication, a monoclonal antibody that targets the HER2 receptor in HER2-positive breast cancer 2 . Ado-trastuzumab emtansine (T-DM1), an antibody-drug conjugate (ADC) that combines trastuzuman...

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